Volume: 3 Issue: 2, 9/16/22

Year: 2022

Research Articles

Assoc. Prof. Fazile Nur EKİNCİ AKDEMİR AĞRI İBRAHİM ÇEÇEN ÜNİVERSİTESİ 0000-0001-9585-3169
Medical Physiology
Medical Pharmacology, Medical Physiology
Assoc. Prof. Dr. Afak DURUR KARAKAYA Koc University, Faculty of Medicine, Department of Radiology
Radiology and Organ Imaging
Health Sciences
Aslı ÖZBEK BİLGİN Erzincan Binali Yıldırım Universiy
İlhami GÜLÇİN Atatürk University
Khalid JAVED Lahore University
Yasin BAYIR Atatürk University
Dr. Tuğba GÜLER SELÇUK ÜNİVERSİTESİ, TIP FAKÜLTESİ
Pediatric Immunology and Allergic Diseases
Ayhan TANYELİ Atatürk University
Hilal KIZILTUNÇ ÖZMEN Atatürk University

Aim
New Trends in Medicine Sciences (NTMS) provides a forum for scientists, researchers, and academicians to share their ideas and new research in the field of medical sciences and their applications. NTMS is a high-quality double-blind refereed journal. NTMS is also a multidisciplinary research journal that serves as a forum for individuals in the field to publish their research efforts and interested readers to acquire the latest development information in the field. NTMS facilitates communication and networking among researchers and scientists when considerable changes are taking place in scientific innovation. It provides a medium for exchanging scientific research and technological achievements accomplished by the international community. 

NTMS is an open-access journal that publishes articles in accordance with the open-access model based on the Budapest Open Access Initiative (BOAI) Declaration. 

The definition of OA introduced in the original BOAI:

"By open access" to (peer-reviewed research literature), we mean its free availability on the public internet, permitting any users to read, download, copy distribute, print, search, or link to the full texts of these articles, crawl them for indexing, pass them as data to software, or use them for any other lawful purpose, without financial, legal, or technical barriers other than those inseparable from gaining access to the internet itself. The only constraint on reproduction and distribution, and the only role for copyright in this domain, should be to give authors control over the integrity of their work and the right to be properly acknowledged and cited."

You can reach the BOAI at the below:

The Budapest Open Access Initiative

Creative Commons License
The content published in NTMS is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Thereby you transfer your copyright to NTMS.

You are free to:

Share — copy and redistribute the material in any medium or format

But,

NonCommercial — You may not use the material for commercial purposes

NoDerivatives — If you remix, transform, or build upon the material, you may not distribute the modified material


Scope

NTMS aimed to be an academic and scientific platform established to evaluate the studies in medical disciplines and provide access to international scientists. NTSM is published in English as two issues in a year (in September and October) and aims to publish special issues about current issues. Our journal is available in Ulakbim, Dergipark Web portal. It prioritizes disciplines in the basic, internal and surgical sciences of medicine and publishes clinical and experimental studies. Briefly, NTSM deals with general medicine, including several fields, as mentioned below.
* Basic Medical Sciences
- Anatomy
- Biophysics
- Biostatistics
- Physiology
- Histology and Embryology
- Medical Biochemistry
- Medical Biology
- Medical Education and Informatics
- Medical Microbiology
- Medical History and Ethics
* Internal Medicine
- Emergency Medicine
- Family Medicine
- Forensic Medicine
- Infectious Diseases and Clinical Microbiology
- Medical Genetics
- Medical Pharmacology
- Neurology
- Chest Diseases
- Nuclear Medicine
- Pediatrics
- Public Health
- Radiation Oncology
- Radiology
- Sports Medicine
- Child and Adolescent Psychiatry
- Dermatology and Venereology Thoracic
- Dermatology
- Cardiology
* Surgical Medicine Sciences
- Anesthesiology and Reanimation
- Pediatric Surgery
- General Surgery
- Chest Surgery
- Cardiovascular and Thoracic
- Ophthalmology
- Obstetrics and Gynecology
- Otorhinolaryngology
- Neurosurgery
- Orthopedics and Traumatology
- Medical Pathology
- Plastic Reconstructive and Aesthetic Surgery
- Urology 

Please read these instructions before submitting your article.

A. General Policy:

The articles or contents sent to our journal should not have been published in any way before and should not be evaluated simultaneously by another journal. The corresponding author declares that all co-authors have seen and approved the article's final version for the submitted article. The articles are only accepted to be published because the authors will allow editorial changes. Still, the final reading and proof of the article are sent to the responsible author before being sent to the press. The decision to accept/reject an article belongs to the NTMS Editorial Board. "All processes related to preliminary evaluation, referee reviews, and publishing in our journal depend on the quality of the article you submitted, the result of the plagiarism report, and the sufficiency of the English language.

Types of articles: Articles will be evaluated for publication in Research Articles based on clinical and experimental studies, Reviews, Case Reports, Short Communications, and Editorial Letters.

The average time during which the preliminary assessment of manuscripts is 15 days. The average time during which the reviews of manuscripts are 90 days. The average time in which the article is published is 180 days.

The study submitted to NTMS should be original, prepared according to the writing rules and instructions of NTMS by an authoritative person and/or people who contribute in a related field and bring a new breath to the relevant field.

The text of the article (including the English title, Abstract, Keywords, Introduction, Materials and Methods, Results, Discussion, Conclusion, References, and Figure descriptions) should be submitted as a text file in .doc format. Tables (doc) and Figures should be presented after references as .jpg, .eps or .tiff. The entire text file should be prepared in Times New Roman font, including table and figure captions/descriptions.


Preparation of the article:
1. The publication language of the journal is English.
2. Article text should be written in 12-point Times New Roman font, single-spaced with 2.5 cm margins on each side.
3. Each page should be numbered at the bottom right corner.

4. The abbreviations should be in parenthesis during the first mentioned in the text and used in all articles.

5. If a drug, medical agent, extract, species names are used, or a special technique is mentioned, it should be written in italics (for example, Graptophyllum pictum, E.coli).

6. All authors must declare with certainty whether there are any real or potential conflicts of interest, including financial, personal, or other relationships with other persons or organizations that may inappropriately influence their work.
7. The text should be organized with the following headings: Title; Abstract; Keywords; Introduction; Materials and Methods; Results; Discussion; Conclusion; Acknowledgement; Conflict of Interest; Financial support; and References.
8. Title page should include the article's main title and short title, authors’ names, the name of the institutions, ORCIDs, addresses, and e-mail addresses for all authors. On the bottom, give the corresponding author's full name, address, ORCIDs, and e-mail address.
9. An Abstract of not more than 300 words together with 3-5 keywords chosen from the Medical Subject Headings (MeSH) list is to be provided directly below the abstract. Keywords should express the manuscript's precise content. They are used for indexing purposes. Provide abbreviations and nomenclature lists in alphabetical order and non-standard ones in the manuscript (excluding references) with definitions after the keywords. If needed, the abbreviations used in the text with their full explanations could be listed here, too.
10. It is necessary not to use abbreviations in the abstract and to give references.

11. Subdivision - unnumbered sections Divide your article into clearly defined sections. Each subsection is given a brief heading. Each heading should appear on its own separate line. Subsections should be used as much as possible when the cross-referencing text refers to the subsection by heading instead of simply 'the text.'

Introduction
State the objectives of the work and provide an adequate background, avoiding a detailed literature survey or a summary of the results.
Materials and methods
Provide sufficient details to allow the work to be reproduced by an independent researcher. Methods that are already published should be summarized and indicated by a reference. If quoting directly from a previously published method, use quotation marks and also cite the source. Any modifications to existing methods should also be described.
Results
Results should be clear and concise.
Discussion
This should explore the significance of the results of the work, not repeat them. A combined Results and Discussion section is often appropriate. Avoid extensive citations and discussion of published literature.
Conclusions
The study's main conclusions may be presented in a short Conclusions section, which may stand alone or form a subsection of a Discussion or Results and Discussion section.
Appendices
If there is more than one appendix, they should be identified as A, B, etc. Formulae and equations in appendices should be given separate numbering: Eq. (A.1), Eq. (A.2), etc.; in a subsequent appendix, Eq. (B.1), and so on. Similarly, for tables and figures: Table A.1; Fig. A.1, etc.

Abbreviations
Define abbreviations that are not standard in this field in a footnote to be placed on the article's first page. Such abbreviations that are unavoidable in the abstract must be defined at their first mention there and in the footnote. Ensure consistency of abbreviations throughout the article.


Permissions
Authors wishing to include figures, tables, or text passages that have already been published elsewhere are required to obtain permission from the copyright owner(s) for both the print and online format and to include evidence that such permission has been granted when submitting their papers. Any material received without such evidence will be assumed to originate from the authors. For the Copyright Agreement Form, click here


Title Page
The title page should include:
· The name(s) of the author(s)
· A concise and informative title
· The affiliation(s) and address(es) of the author(s)
· The e-mail address, and telephone of the corresponding author


Abstract
Please provide an abstract of 250 to 300 words. The abstract should not contain any undefined abbreviations or unspecified references.


Keywords
Please provide 3 to 5 keywords in accordance with Index Medicus Medical Subject Headings (MeSH) that can be used for indexing purposes.


Headings
Please use no more than three levels of displayed headings.


Abbreviations
Abbreviations should be defined at first mention and used consistently thereafter.


Footnotes
Footnotes can give additional information, including the citation of a reference in the reference list. They should not consist solely of a reference citation and should never include the bibliographic details of a reference. They should also not contain any figures or tables.
Footnotes to the text are numbered consecutively; those to tables should be indicated by superscript lower-case letters (or asterisks for significance values and other statistical data). Footnotes to the title or the article's authors are not given reference symbols.
Always use footnotes instead of endnotes.

Acknowledgments
Acknowledgments of people, grants, funds, etc., should be placed in a separate section before the reference list. The names of funding organizations should be written in full.

References
Number references consecutively in the order in which they are first mentioned in the text. Identify references in the text, tables, and legends using superscripted Arabic numerals placed after the punctuation.
Use the Vancouver reference system adopted by the U.S. National Library of Medicine, ensuring all journal titles conform to Index Medicus-approved abbreviations. If in doubt, look up the reference list of a recent paper published in the New Trends in Medicine Sciences.
Avoid citing abstracts unless from a MEDLINE or EMBASE indexed journal.
Authors must confirm that the details of these references are accurate and complete. In the full list of references, give the names and initials of all authors. Cite only the first three names followed by et al. The authors' names are followed by the title of the article: the title of the journal (italics) abbreviated according to the style of Index Medicus: the year of publication (in bold): the volume number: the first and last page numbers in full followed by a full stop. Titles of books should be followed by the town and country of publication, the publisher, the year (bold), and inclusive page numbers. See the following examples:
Journals articles:
Ekinci Akdemir FN, Yildirim S, Kandemir FM, et al. The effects of casticin and myricetin on liver damage induced by methotrexate in rats. Iran J Basic Med Sci 2018; 21:1281-1288
Ahiskalioglu A, Yayik AM, Celik EC, et al. Ultrasound-guided modified Thoracolumbar Interfascial Plane block for low back pain management. J Clin Anesth 2019; 54:138-139
Books:
Haggis GH: The structure and function of membranes (Eds. GH Haggis, D Michie, AR Muir, KB Roberts and PMB Walker). In: Introduction to Molecular Biology. Longmans, London: 1964, 151–192.
Chapter in a book:
Pessayre D, Feldmann G, Haouzi D, et al. Hepatocyte apoptosis triggered by natural substances (cytokines, other endogenous molecules, and foreign toxins). In Cameron RG, Feuer G (editors): Apoptosis and its Modulation by Drugs. Handbook of Experimental Pharmacology. Berlin: Springer-Verlag; 2000, pp. 59-108.
Web Page:
Cancer Research UK. Cancer statistics reports for the UK, http://www.cancerresearchuk.org/aboutcancer/statistics/cancerstatsreport/; 2003 [accessed 13 March 2003].

Supplementary material

Authors may send supplementary images, tables, figures, videos, copyright transfer forms, ethical approval, and plagiarism report to be added online.
Submission Preparation Checklist
As part of the submission process, authors must check off their submission's compliance with all of the following items, and submissions may be returned to authors that do not adhere to these guidelines.
1- The submission has not been previously published, nor is it before another journal for consideration (or an explanation has been provided in Comments to the Editor).
2- The submission file must be prepared according to the journal's rules.
3- The text is in single-column format; uses a 12-point font; employs italics, rather than underlining (except with URL addresses); and all illustrations, figures, and tables are placed within the text at the appropriate points, rather than at the end.

Copyright Notice
All the intellectual property rights of the papers accepted for the publication belong to New Trends in Medicine Sciences (NTMS).

The corresponding author will receive proofs by e-mail in PDF format. Authors are requested to check the proofs and return any corrections within 48 hours. The corresponding author, at no cost, will obtain a PDF file of the article via e-mail.


Privacy Statement
The names and email addresses entered in this journal site will be used exclusively for the stated purposes of this journal. They will not be made available for any other purpose or to any other party.

ETHICAL RULES AND PUBLISHING PRINCIPLES

New Trends in Medicine Sciences (NTMS) has adopted the development and distribution of information impartially and respectably. In the process of publication, authors expect readers, researchers, publishers, referees, and editors to abide by the ethical rules. These stakeholders should pay attention to the standard general and specific ethical rules and responsibilities shared below, according to the open-access guides published by Higher Education Institutions (YÖK), International Medical Journals Editors Board (ICMJE)Committee on Publication Ethics (COPE), and  DOAJ-Principles of Transparency and Best Practice in Scholarly Publishing.

1. SCIENTIFIC RESEARCH AND GENERAL ACTIONS OPERATING AGAINST PUBLICATION ETHICS

a) Plagiarism: Presenting others' ideas, methods, data, applications, writings, forms, or works as if they were their work, without reference to scientific, ethical rules,
b) Fraud: To produce data that is not based on research, to edit or change the submitted or published work based on unrealistic data, to report or publish them, to show undone research as done,
c) Distortion: To falsify research records and obtained data, to show methods, devices, and materials that are not used in the research as used, to evaluate data that do not comply with the research hypothesis, to play with data or results in line with the interests of individuals and organizations that are supported. Distorting or shaping research results,
d) Duplicate Publication: To present more than one work containing the same results of research as separate works in professorship exam evaluations and academic promotions,
e) Slicing: To present the results of research as separate works in certain exam evaluations and academic incentives and promotions, disrupting the integrity of the research, disassembling it inappropriately, and making numerous publications without reference to each other,
f) Unfair Authorship: Adding people who do not have an active contribution to article authors, not including people who have an active contribution among the authors, changing the author's order unjustly and inappropriately, removing the names of those who have an active contribution from work during publication or in subsequent editions, using their influence even though they do not have an active contribution to include the name among the authors,
g) Other Types of Ethical Violation: It is assigned not to clearly state the contributions of individuals, institutions, or organizations and their support in the publications of the research carried out with the support of the research, not to respect the ethical rules in the researches conducted on human and animals, to respect the rights of the patients in their publications, to examine them as referees. To share the information in work with others before publication, to use the resources, places, facilities, and devices for scientific research other than the purpose, to blame an absolutely groundless, unwarranted, and deliberate ethical violation (YÖK Scientific Research and Publication Ethics Directive)

2. STAKEHOLDERS' RESPONSIBILITIES

a) Responsibilities of Editors

Based on NTMS editor and assistant editors, Code of Conduct and Best Practice Guidelines for Journal Editors, and the Best Practice Guidelines for Journal Editors published by Committee on Publication Ethics (COPE) will provide ethical duties and responsibilities:

- Editors are responsible for every publication published in NTMS.
- Editors have the responsibility and authority to accept or reject articles. It has to use this responsibility and authority in place and on time.
- Editors should not conflict with interest regarding articles they accept or reject.
- Editors should accept original articles that will contribute to their field.
- Editors should reject incomplete and erroneous researches that do not comply with journal policy, publishing rules, and level without any influence.
- Editors should allow the wrong, incomplete and problematic articles to be withdrawn before or after the referee report or published after they are corrected.
- Editors ensure that the articles evaluated by at least two referees are assessed according to the double-sided blind review system and keep the referees confidential.
- Editors continue their business processes without sacrificing intellectual property rights and ethical standards.
- The editors take responsibility for the plagiarism status of the articles and whether they are unpublished or original research through the "Turnitin and/or ithenticate" plagiarism program.
- Editors consider the knowledge, skills, and experiences needed by all readers, researchers, and practitioners.
- Editors take care that the published issues contribute to the reader, researcher, practitioner, and scientific field and be original.
- Editors ensure that all advisory committee members advance the processes by their editorial policies and guidelines.
- Editors inform the members of the advisory board about their publication policies.
- Editors allow members of the advisory board to evaluate their work independently.
- Editors can contribute to new advisory board members and make decisions accordingly.
- Editors should submit appropriate studies with the expertise of advisory board members for evaluation.
- Editors regularly interact with the advisory board.
- Editors organize regular meetings with the editorial board for publishing policies and journal development.
- The relationship between editors (Editor and Co-Editors) and publishers is based on the principle of editorial independence. According to the written agreement between the editors and the publisher, all the editors' decisions are independent of the publisher and the journal owner.
-Editors and Associate Editors can not print more than four(4) articles in NTMS.

b) Authors' Responsibilities

- It is expected that the works submitted by the author (s) should be original. If the author (s) benefit from or use other studies, they should cite and/or quote entirely and accurately.
-People who do not contribute to the content intellectually in creating the study should not be specified as authors.
- The situations and relationships of all the studies that may constitute a conflict of interest must be explained.
- The raw data on their articles may be requested from the author(s) within the evaluation processes. In such a case, the author (s) should be ready to present the expected data and information to the editorial board and scientific board.
-The author (s) must have a document showing that they have the rights to use the data used, the necessary permissions for the research /analysis, or the consent of the experimental subjects has been obtained.
- If the author (s) notices a mistake or error related to the published article at the early view or evaluation stage, it must cooperate with the editor in informing, correcting, or withdrawing the journal editor or publisher.
- The study of authors can not simultaneously have in the application process of more than one journal. Each application can be started following the completion of the previous application. A published study in another journal cannot be sent to us.
- Change of author responsibilities (such as adding author, changing author order, removing author) cannot be offered for a study whose evaluation process has started.

c) Responsibilities of Arbitrators
Our journal management is committed to successfully executing and improving the refereeing process within the framework of ethical publishing rules. Welcomes the stakeholders and readers of the research to report their plagiarism, repeated publications, inaccuracies, suspicious content, or situations to the e-mail address ntms.editor@gmail.com. It reports the data and results obtained on the subject to the relevant parties and follows them. It is based on the referees' compliance with the following principles.

- Evaluations should be done impartially.
- There should be no conflict of interest between the referees and the stakeholders of the article under consideration.
- Completion of other articles, works, sources, citations, rules, and similar deficiencies related to the article should be pointed out.
- Articles or referees evaluated based on the double-sided blind review system are not disclosed.

3. PLAGIARISM POLICY
New Trends in Medicine Sciences (NTMS) demands a plagiarism (Turnitin or iThenticate) report for each submission attempt. If the corresponding author does not provide this document, it will be performed by the journal itself. Studies with plagiarism above 20% are not evaluated and returned to the author. If a study published in the journal is found to be plagiarism, the Editorial Board withdraws the article and initiates the necessary actions.

4. PROTECTION OF PERSONAL DATA
Editors ensure the protection of personal data on the topics or images included in the evaluated work. Documents showing their contributions are given to the contributors (editors, authors, and referees).

5. ETHICAL COMMITTEE, HUMAN AND ANIMAL RIGHTS
Editors ensure the protection of human and animal rights in the evaluated works. Editors have the responsibility to refuse to work when the ethics committee consents to the issues used in the study, and there is no permission for experimental research. In studies requiring ethics committee permission, information about the permit (board name, date, and number no) should be included in the method section and on the first/last page of the article. In case reports, information about the informed volunteer/consent form being signed should be included in the article.

6. POSSIBLE ABUSE AND ABUSE MEASURES
Editors take precautions against possible abuse and abuse behavior. In addition to conducting a rigorous and objective investigation into the detection and evaluation of complaints related to this situation, the editor's responsibilities share the relevant findings with the competent authorities.

7. PROVIDING ACADEMIC PUBLISHING INTEGRITY
Editors ensure that the decisions involving errors, inconsistencies, or misleading in the works are corrected quickly.

8. PROTECTION OF INTELLECTUAL PROPERTY RIGHTS
Editors are obliged to take necessary measures to protect the intellectual property rights of all published articles and defend journal and author rights in case of possible violations to ensure that the content of all published articles does not violate the intellectual property rights of other publications.

9. CONFIGURATION AND OPEN DISCUSSION
The editors take into account the criticism against the works published in the journal and take a constructive attitude towards these criticisms in line with the purpose and scope of the journal. Authors of criticism have the right to reply. Studies with negative results are rejected.

10. COMPLAINTS
Editors must review the complaints carefully and respond to the authors, reviewers, or readers in an enlightening and explanatory manner.

11. POLITICAL AND COMMERCIAL CONCERNS
The owner, publisher, and any other political or commercial element cannot influence the magazine's editorial decisions.

12. CONFLICTS OF INTEREST
Editors guarantee and provide authors and referees that the journal's publication process will be maintained independently and impartially.


NTMS
PUBLICATION POLICY and PUBLICATION PROCESS

1- Journal Section Policies:

Research Article, Short Articles, Technical Note, Case Reports, Letters to the Editor

2- Open Access Policy:
New Trends in Medicine Sciences (NTMS) provides open access for the continuous and free use of its content to increase the global change of knowledge and to produce beneficial results for humanity. In this context, all articles published in the journal are available at https://dergipark.org.tr/tr/pub/ntms/archive. The articles in NTMS are licensed under the Creative Commons Attribution-NonCommercial 4.0 International License. Commercial use of the content is prohibited. Articles in the journal can be used as long as the author and original source are cited.

3- Pricing Policy:
New Trends in Medicine Sciences (NTMS) does not charge any fee for the articles' submission, evaluation, and publication. The authors do not pay article processing fees for the works they send to the journal.

4- Article Evaluation Process:
New Trends in Medicine Sciences (NTMS) is published twice a year, in April and October. All of the articles are published in a collective number, with a table of contents.

a) Articles are written following NTMS writing rules and uploaded to the journal system by the responsible author.
b) The received article NTMS is delivered to the editor (2-5 days) after editorial review by assistant editors.
c) It is forwarded to the related referees (5-10 days) according to the article's subject, reviewed by the editor, and approved.
d) Studies are sent to at least two referees. If one of the referees gives a negative report, the study is recommended to the 3rd referee.
e) The authors are informed according to the referee reports (within one month at the latest).
f) The articles that require correction should be corrected and sent back following the reports within one month at the latest.
g) In case of acceptance from two referees, the article is published in the following number.
h) The publication decision process between 1 and 2 months after submitting an article to NTMS is concluded.

New Trends in Medicine Sciences does not charge any fee for article submission or other process operations per its publication policy and continues its publication life free of charge.